Hot Chocolate May Prevent
Memory Decline
Scientists think there could be a
link between hot chocolate and brain blood flow
Scientists at Harvard
Medical School suggest drinking two cups of hot chocolate a day may keep the
brain healthy and prevent memory decline in older people by preserving blood
flow in working areas of the brain.
They write about their findings
online in the August 7th issue of Neurology.
The team was investigating the
effect of cocoa consumption on thinking and memory performance, as well as
something called neurovascular coupling, where blood flow in the brain changes
in response to local brain activity.
"As different areas of the
brain need more energy to complete their tasks, they also need greater
blood flow. This relationship, called neurovascular coupling, may play an
important role in diseases such as Alzheimer's."
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For their investigation, the team recruited 60 dementia-free
older people of average age 73 and asked them to drink two cups of hot cocoa a
day for 30 days.
Half the participants drank hot cocoa high in
antioxidant flavanol, while the other half drank flavanol-poor hot cocoa.
(There is substantial evidence that consuming cocoa flavanols helps circulation
and heart health.
The participants were asked not to consume any other
products containing chocolate during the study.
The team tested the participants' memory and thinking
skills before and after using a set of standard tests.
Using ultrasound, they also
measured neurovascular coupling (the blood flow response to brain activity) as
the participants completed the mental tests.
At the start of the study, 18 of the 60 participants
had impaired neurovascular coupling. By the end of the study, it had improved
by 8.3%.
These participants also improved their scores on a
working memory speed test. At the start of the study, it took them 167 seconds
to complete the test, while at the end they did it in 116 seconds.
In participants with regular neurovascular coupling at
the start of the study, there was no change either in blood flow measures or
working memory.
A subset of 24 participants also underwent MRI scans to look for tiny areas of damage in the white
matter of the brain. These can occur when there is a restriction in blood flow.
The MRI scans showed that the participants with
impaired neurovascular coupling were the ones most likely to have these tiny
areas of brain damage.
There was no difference between the participants who
drank flavanol-rich cocoa and the ones who drank flavanol-poor cocoa.
In their study paper, Sorond and colleagues conclude:
"There is a strong correlation
between neurovascular coupling and cognitive function, and both can be improved
by regular cocoa consumption in individuals with baseline impairments. Better
neurovascular coupling is also associated with greater white matter structural
integrity."
In an editorial accompanying the
team's study report, Paul B. Rosenberg, an Alzheimer's expert at Johns Hopkins
School of Medicine in Baltimore, MD, says the study is an important first step,
but:
"More work is needed to prove
a link between cocoa, blood flow problems and cognitive decline."
A research review of 20 trials that
was published in The Cochrane Library in 2012, found that consuming
dark chocolate or cocoa
may reduce blood pressure by a
small amount.
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